Invasion of the caterpillars

Caterpillars are everywhere right now. They only seem to 'blossom' every few years or so because I don't remember seeing them around the house since we moved in. I can remember them taking over the apple and plum trees at my childhood home. White tents would span the branches as they nibbled away on the leaves. I don't know if I should be concerned that they are crawling all over the house or not. Will they find five coats of Drum Beat Red tasty?